ORIGINAL RESEARCHeffect of polyphenols On blood SUGAR control
A mechanistic investigation into the acute effects of apple polyphenols on carbohydrate digestion and absorption.
research questionFood and beverages containing large amounts of highly bioaccessible starch and sugars induce pronounced postprandial blood glucose concentrations. Chronic exposure to exaggerated sharp peaks in blood glucose can lead to adverse modifications to functional proteins, oxidative stress and pancreatic ß-cell dysfunction, thereby increasing the risk of cardiometabolic diseases. Previous research by our group demonstrated that 1.8 g of polyphenol-rich apple attenuated the early postprandial glucose response to a high-carbohydrate meal.
Does an apple a day keep type 2 diabetes away?
The overarching aim of this research project was to present evidence to support the acute gluco-modulatory mechanisms of a polyphenol-rich apple extract (AE), carried out in three phases. In vitro experiments and a randomised controlled trial demonstrated that the AE, even at a low dose, can delay early-phase glycemia. Both the inhibition of alpha-amylase and glucose uptake are likely two important mechanisms which can explain the glucoregulatory properties of the AE. The full report of this research can be found here.
SOME KIND WORDSI have known emily since she was a phD student at king’s and witnessed her passion for nutrition science together with her talent for public speaking. she has continued to hone her craft as a nutrition scientist and communicator and i am thrilled to see where her career has taken her.
DR sarah berry KING'S COLLEGE LONDON
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